方法证据记录
PET Kinetic Modeling
PET kinetic modeling is a quantitative analysis technique that tracks the temporal behavior of radioactive tracers in tissue to extract physiological parameters such as blood flow, metabolic rate, and receptor density. Established by Patlak, Logan, and Gunn in the 1980s and 1990s, kinetic modeling transforms raw PET time-activity curves into interpretable biological measures. It is widely used in neurology, oncology, and cardiology to assess disease severity, treatment response, and regional tissue function.
源记录
引文逐字复制自方法源记录。这些引文不代表任何层级的验证。
Positron Emission Tomography Kinetic Modeling
分类方法记录 · process-pipeline / medical-imaging
- Patlak, C. S., Blasberg, R. G., Fenstermacher, J. D. (1983). Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. Journal of Cerebral Blood Flow & Metabolism, 3(1), 1-7. · DOI 10.1038/jcbfm.1983.1
- Logan, J., Fowler, J. S., Christman, D. R., et al. (2000). Graphical analysis of reversible radioligand binding from time-activity measurements applied to [N-11C]cocaine PET studies in human subjects. Journal of Cerebral Blood Flow & Metabolism, 10(5), 740-747. · URL
- Gunn, R. N., Gunn, S. R., Cunningham, V. J. (2001). Positron emission tomography compartmental models. Journal of Cerebral Blood Flow & Metabolism, 21(6), 635-652. · DOI 10.1097/00004647-200106000-00002
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