方法证据记录

Adaptive Randomized Controlled Trial

An adaptive randomized controlled trial (adaptive RCT) is an experimental design in which pre-specified rules allow modifications to the trial while it is ongoing — such as changing allocation ratios, dropping underperforming arms, or stopping early for efficacy or futility — based on accumulating interim data. These adaptations are planned before the trial starts and governed by statistical rules to preserve Type I error control and validity.

Sources recorded, not reviewed

源记录

引文逐字复制自方法源记录。这些引文不代表任何层级的验证。

分类方法记录 · process-pipeline / experimental-design

Chow, S.-C., & Chang, M. (2008). Adaptive Design Methods in Clinical Trials. Chapman & Hall/CRC. · ISBN 978-1584887690
Berry, D. A. (2006). Bayesian clinical trials. Nature Reviews Drug Discovery, 5(1), 27–36. · DOI 10.1038/nrd1927

打开完整方法

精选声明

声明已持久化到证据分类账中，每个声明都有自己的评估。

尚无精选声明

当分类账中没有声明时，此视图不会自行创建声明评估。

相关方法

从方法图中生成，显示为机器建议的关系 — 不推断任何证据声明。

Taxonomic bucketAdaptive Experimentmachine-suggested · Relational suggestion, not evidence.See alsoBayesian Inferencemachine-suggested · Relational suggestion, not evidence.Taxonomic bucketFactorial Randomized Controlled Trialmachine-suggested · Relational suggestion, not evidence.Taxonomic bucketMulti-arm experimentmachine-suggested · Relational suggestion, not evidence.Used in the same domainRandomized Controlled Trialmachine-suggested · Relational suggestion, not evidence.See alsoSequential Analysismachine-suggested · Relational suggestion, not evidence.