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| Windkessel模型× | CFD 血液动力学× | |
|---|---|---|
| 领域 | 生物力学 | 生物力学 |
| 方法族 | Process / pipeline | Process / pipeline |
| 起源年份≠ | 1969 | 2002 |
| 提出者≠ | Nikolaos Westerhof | David Steinman |
| 类型≠ | Physiological lumped-parameter modeling | Multi-physics finite element simulation |
| 开创性文献≠ | Westerhof, N., Bosman, F., De Vries, N. C., & Noordergraaf, A. (1969). Analog studies of the human systemic arterial tree. Journal of Biomechanics, 2(2), 121-143. DOI ↗ | Steinman, D. A., Vinh, B., Ethier, C. R., Ojha, M., Cobbold, R. S., & Johnston, K. W. (2002). A numerical simulation of flow in a two-dimensional end-to-side anastomosis model. Journal of Biomechanical Engineering, 115(1), 112-118. link ↗ |
| 别名 | Elastic chamber model, Arterial compliance model, Lumped parameter model | Cardiovascular CFD, Blood flow simulation, Hemodynamic simulation |
| 相关 | 3 | 3 |
| 摘要≠ | The Windkessel model is a lumped-parameter representation of the arterial system that captures the pulsatile dynamics of blood flow and pressure using simple mechanical analogs (resistors and capacitors). Named after the German word for air chamber, it was formalized by Westerhof and colleagues in the late 1960s and remains fundamental to understanding arterial hemodynamics and blood pressure regulation. | Computational fluid dynamics (CFD) for hemodynamics solves the Navier-Stokes equations to simulate blood flow in realistic vascular geometries. Pioneered by researchers such as David Steinman, CFD hemodynamics reveals complex flow patterns, wall shear stress distributions, and hemodynamic factors implicated in atherosclerosis, aneurysm rupture, and device-induced thrombosis. |
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