方法对比

	单盲前测-后测实验设计	单盲随机对照试验
领域	实验设计	实验设计
方法族	Process / pipeline	Process / pipeline
起源年份	1963 (systematic codification); blinding in use from early 20th century	1948 (formalized); single-blind variant established in mid-20th century clinical trial methodology
提出者	Campbell & Stanley (codified); blinding practice has earlier roots in clinical research	Bradford Hill and colleagues (MRC streptomycin trial, 1948); blinding conventions codified in CONSORT guidelines
类型	Controlled experimental design with partial blinding	Experimental design — blinded randomized trial
开创性文献	Campbell, D. T., & Stanley, J. C. (1963). Experimental and Quasi-Experimental Designs for Research. Rand McNally.	Schulz, K. F., Altman, D. G., Moher, D., & CONSORT Group. (2010). CONSORT 2010 statement: Updated guidelines for reporting parallel group randomised trials. BMJ, 340, c332.
别名	single-masked pretest-posttest design, participant-blind pretest-posttest, single-blind before-after design, SB-PP design	single-masked RCT, single-blind RCT, single-blind trial, SB-RCT
相关	6	5
摘要	The single-blind pretest-posttest experimental design combines two protective strategies: measuring outcomes both before and after treatment to quantify change, and keeping participants unaware of which condition they are in. This pairing controls for preexisting group differences and expectancy-driven response bias, making it a practical middle ground between fully open-label and double-blind trials in behavioral and health research.	A single-blind randomized controlled trial (SB-RCT) is a rigorous experimental design in which participants are randomly assigned to treatment or control conditions while remaining unaware of which condition they have received. Investigators, outcome assessors, and data analysts are not blinded. By masking participants, the design eliminates placebo and nocebo response biases on the participant side, while preserving investigator flexibility to administer and monitor the intervention.