方法对比

	单盲多臂试验	析因实验
领域	实验设计	实验设计
方法族	Process / pipeline	Process / pipeline
起源年份	Mid-to-late 20th century	1926–1935
提出者	Developed within the clinical trials tradition; formalized by Friedman, Furberg, and DeMets and others in the 20th century	Ronald A. Fisher
类型	Controlled experimental design	Quantitative experimental design
开创性文献	Friedman, L. M., Furberg, C. D., & DeMets, D. L. (2010). Fundamentals of Clinical Trials (4th ed.). Springer. ISBN: 978-1441915849	Fisher, R. A. (1935). The Design of Experiments. Oliver and Boyd.
别名	single-masked multi-arm trial, single-blind multi-group experiment, unidirectional blinding multi-arm design, SB-MAT	factorial design, factorial ANOVA design, multi-factor experiment, crossed-factor design
相关	5	6
摘要	A single-blind multi-arm experiment is a controlled experimental design that simultaneously compares three or more treatment conditions while blinding participants — but not investigators — to their group assignment. This configuration reduces response bias driven by participants' expectations, preserves operational feasibility when full blinding is impractical, and allows direct pairwise and omnibus comparisons across multiple arms within a single study.	A factorial experiment is an experimental design in which two or more independent variables (factors) are manipulated simultaneously, and every combination of their levels is tested. Introduced by Ronald Fisher in the 1920s–1930s, it is the standard approach whenever a researcher needs to detect not only the main effect of each factor but also whether the effect of one factor depends on the level of another — the interaction effect.