方法对比

	单盲全因子实验	区组完全析因实验
领域	实验设计	实验设计
方法族	Process / pipeline	Process / pipeline
起源年份	Full factorial: 1935 (Fisher); single-blind clinical convention: mid-20th century	1935 (Fisher); systematized through 20th-century DOE literature
提出者	Full factorial framework: R. A. Fisher; single-blind masking practice: clinical trial tradition, standardized by the 20th century	R. A. Fisher (blocking principle); full factorial DOE tradition
类型	Controlled experimental design	Experimental design
开创性文献	Montgomery, D. C. (2017). Design and Analysis of Experiments (9th ed.). Wiley. ISBN: 978-1119113478	Montgomery, D. C. (2017). Design and Analysis of Experiments (9th ed.). Wiley. ISBN: 978-1119113478
别名	single-masked full factorial, single-blind complete factorial, SB-FFE, single-blind all-combinations design	blocked full factorial design, full factorial with blocking, complete factorial blocked design, BFF design
相关	6	4
摘要	A single-blind full factorial experiment systematically tests every combination of all factor levels while keeping participants unaware of their treatment assignment. This design allows simultaneous estimation of all main effects and all interaction effects between factors, with single-blind masking reducing participant-side biases such as demand characteristics and expectation effects — without requiring investigator blinding.	A blocked full factorial experiment tests every combination of all factor levels while grouping experimental runs into homogeneous blocks to isolate a known nuisance variable. This design preserves the power to detect all main effects and interactions of the factors of interest while preventing batch-to-batch, day-to-day, or machine-to-machine variability from inflating experimental error.