方法对比
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| 回顾性Cox比例风险模型× | 生存分析× | |
|---|---|---|
| 领域≠ | 流行病学 | 研究统计学 |
| 方法族 | Process / pipeline | Process / pipeline |
| 起源年份≠ | 1972 | 1958 |
| 提出者≠ | David R. Cox | Edward L. Kaplan and Paul Meier |
| 类型≠ | Semi-parametric survival regression | Method |
| 开创性文献≠ | Cox, D. R. (1972). Regression models and life-tables. Journal of the Royal Statistical Society, Series B, 34(2), 187–220. DOI ↗ | Kaplan, E. L., & Meier, P. (1958). Nonparametric estimation from incomplete observations. Journal of the American Statistical Association, 53(282), 457–481. DOI ↗ |
| 别名≠ | Cox PH regression (retrospective), retrospective Cox survival model, retrospective hazard regression, Cox model on historical data | Kaplan-Meier analysis, Cox regression, TTE analysis |
| 相关≠ | 5 | 3 |
| 摘要≠ | Retrospective Cox proportional hazards regression applies Cox's (1972) semi-parametric survival model to time-to-event data extracted from existing records — medical charts, administrative databases, registries, or biobanks. It estimates covariate-adjusted hazard ratios (HRs) without specifying the underlying baseline hazard, making it the dominant analytic tool when the investigator works backward from already-recorded outcomes and exposures. | Survival analysis is a collection of statistical methods for modeling time from a defined starting point until an event of interest occurs (disease, recovery, death, equipment failure). Kaplan and Meier's nonparametric estimator (1958) and David Cox's proportional hazards model (1972) jointly enabled analysis of censored data—individuals whose event times are unknown because they left the study or were still event-free at follow-up. Indispensable in oncology, cardiology, infectious disease research, engineering reliability, and any field where time-to-event matters. |
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