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| 定量磁化率成像× | 功能性超声× | |
|---|---|---|
| 领域 | 医学影像 | 医学影像 |
| 方法族 | Process / pipeline | Process / pipeline |
| 起源年份≠ | 2015 | 2011 |
| 提出者≠ | Yong Wang | Mickael Tanter |
| 类型≠ | Quantitative MRI contrast mechanism | High-framerate doppler imaging for hemodynamics |
| 开创性文献≠ | Wang, Y., Liu, T. (2015). Quantitative susceptibility mapping (QSM): Decoding MRI data for a tissue magnetic biomarker. Magnetic Resonance in Medicine, 73(1), 82-101. DOI ↗ | Macé, E., Montaldo, G., Trenholm, S., et al. (2011). Functional ultrasound imaging of the brain. Nature Methods, 8(8), 662-664. DOI ↗ |
| 别名≠ | QSM, susceptibility-weighted imaging | fUS, doppler ultrasound, ultrafast ultrasound |
| 相关 | 5 | 5 |
| 摘要≠ | Quantitative Susceptibility Mapping (QSM) is a post-processing technique that converts MRI phase data into quantitative susceptibility values, enabling direct visualization and measurement of tissue magnetic properties. Developed by Wang, Liu, and colleagues, QSM transforms phase shifts caused by differences in magnetic susceptibility between tissues into tissue-specific biomarkers. It has revolutionized the sensitivity of MRI to iron, calcium, and other paramagnetic and diamagnetic substances, making it valuable in neurodegenerative disease diagnosis and tissue characterization. | Functional Ultrasound (fUS) is a high-framerate Doppler ultrasound technique that dynamically maps blood flow and hemodynamic changes in vivo with millisecond temporal resolution. Pioneered by Tanter, Macé, and colleagues in the 2010s, fUS enables real-time imaging of microvascular perfusion in the brain and other organs. By combining ultrafast acquisition (1000-5000 frames per second) with Doppler processing, fUS reveals functional activity (hemodynamic changes during stimulation or behavior) and vascular networks with unprecedented spatiotemporal detail. |
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