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领域流行病学流行病学
方法族Process / pipelineProcess / pipeline
起源年份1978–1999 (foundational frameworks; prospective application standard by 2000s)1958–1972 (foundational methods); prospective design emphasis formalized by 1980s
提出者Fine & Gray (subdistribution hazard model, 1999); Prentice, Kalbfleisch et al. (cause-specific hazard, 1978)Kaplan & Meier (estimator, 1958); Cox (proportional hazards model, 1972); prospective design formalised in modern clinical epidemiology
类型Observational analytic study with event-time statistical analysisLongitudinal observational or experimental study design with time-to-event analysis
开创性文献Fine, J. P., & Gray, R. J. (1999). A proportional hazards model for the subdistribution of a competing risk. Journal of the American Statistical Association, 94(446), 496–509. DOI ↗Kleinbaum, D. G., & Klein, M. (2012). Survival Analysis: A Self-Learning Text (3rd ed.). Springer. ISBN: 978-1441966452
别名prospective CRA, prospective subdistribution hazard analysis, prospective cause-specific hazard analysis, forward-looking competing events analysisprospective time-to-event analysis, prospective failure-time analysis, forward-looking survival study, prospective event-time study
相关45
摘要Prospective competing risks analysis is an observational study design that follows participants forward in time from a well-defined starting point, recording all events — including those that prevent the primary event from occurring — and then estimates cause-specific incidence while correctly accounting for competing outcomes. It combines the temporal clarity of prospective cohort follow-up with the statistical rigor of competing risks methodology to avoid the overestimation inherent in standard Kaplan-Meier curves when multiple event types are present.Prospective survival analysis is a longitudinal study design in which participants are enrolled before the event of interest occurs, followed forward in time under standardised conditions, and analysed using survival-analytic methods to estimate the time until a defined clinical endpoint — such as death, disease recurrence, or treatment failure. Because data are collected prospectively, exposure and covariate information are recorded before outcomes are known, substantially reducing recall and selection bias relative to retrospective approaches.
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ScholarGate方法对比: Prospective Competing Risks Analysis · Prospective Survival Analysis. 于 2026-06-18 检索自 https://scholargate.app/zh/compare