方法对比

	多臂试验可行性测试	多臂实验
领域	实验设计	实验设计
方法族	Process / pipeline	Process / pipeline
起源年份	1990s–2000s	1990s–2000s (clinical formalization); multi-arm concept implicit in ANOVA-era factorial designs
提出者	Evolved from clinical trial methodology; consolidated in the 1990s–2000s	Developed within clinical trials methodology; formalized by Parmar, Royston and colleagues (UK MRC CTU, early 2000s)
类型	Experimental design (pilot/feasibility)	Experimental design
开创性文献	Thabane, L., Ma, J., Chu, R., Cheng, J., Ismaila, A., Rios, L. P., Robson, R., Thabane, M., Giangregorio, L., & Goldsmith, C. H. (2010). A tutorial on pilot studies: The what, why and how. BMC Medical Research Methodology, 10(1), 1.	Royston, P., Parmar, M. K. B., & Qian, W. (2003). Novel designs for multi-arm clinical trials with survival outcomes with an application in ovarian cancer. Statistics in Medicine, 22(14), 2239–2256.
别名	pilot multi-arm trial, feasibility multi-arm study, pilot parallel-arm experiment, preliminary multi-arm experiment	multi-arm trial, multiple-arm experiment, multi-group experiment, many-arm design
相关	6	5
摘要	A pilot multi-arm experiment is a small-scale preliminary trial that tests the feasibility, logistics, and parameter estimates needed to plan a full-scale multi-arm study. It simultaneously evaluates two or more active treatment arms alongside a control, providing early evidence on recruitment rates, retention, protocol adherence, variability, and likely effect sizes before committing to a resource-intensive definitive experiment.	A multi-arm experiment simultaneously compares three or more treatment or intervention conditions — each called an arm — against a shared control or against one another. By testing multiple alternatives in a single study, it yields more information per participant than running separate two-group experiments sequentially, while controlling the overall Type I error rate through pre-specified comparison strategies.