方法对比

	患者总体改善印象 (PGIC)	希恩残疾量表 (SDS)
领域	临床心理学	临床心理学
方法族	Process / pipeline	Process / pipeline
起源年份	1976	1983
提出者	William Guy	David V. Sheehan
类型	Self-report single-item rating	Self-report questionnaire
开创性文献	Guy, W. (1976). ECDEU Assessment Manual for Psychopharmacology. Rockville, MD: National Institute of Mental Health, US Department of Health, Education, and Welfare.	Sheehan, D. V. (1983). The Anxiety Disease. New York: Scribner. ISBN: 9780684183078
别名	PGIC, Patient Global Impression of Change Scale	SDS, Sheehan Disability Scale
相关	4	4
摘要	The Patient Global Impression of Change is a single-item, seven-point rating scale asking patients to report their overall impression of change since treatment initiation. Originally published by William Guy in the ECDEU Assessment Manual in 1976, the PGIC has become a standard co-primary endpoint in clinical trials assessing treatment efficacy. The scale is endorsed by the FDA as a patient-reported outcome measure for demonstrating clinical benefit. Despite its simplicity, the PGIC captures patients' holistic perception of improvement—integrating symptom reduction, functional recovery, and subjective well-being.	The Sheehan Disability Scale is a brief three-item self-report measure designed by David V. Sheehan to assess functional impairment across work/school, social life, and family life domains in psychiatric and medical disorders. First described in Sheehan's 1983 book 'The Anxiety Disease' and validated in multiple studies since, the SDS quantifies the degree to which a patient's illness interferes with major life domains. It is widely used in psychiatric research and clinical practice to assess the functional impact of depression, anxiety, ADHD, and other conditions, complementing symptom severity measures by capturing real-world impairment.