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神经元定向扩散与密度成像 (NODDI)×基于体素的形态学分析×
领域神经影像神经影像
方法族Process / pipelineProcess / pipeline
起源年份20122000
提出者Hui ZhangJohn Ashburner
类型Microstructural white matter mappingStructural MRI gray matter analysis pipeline
开创性文献Zhang, H., Schneider, T., Wheeler-Kingshott, C. A., & Alexander, D. C. (2012). NODDI: practical in vivo neurite orientation dispersion and density imaging of the human brain. NeuroImage, 61(4), 1000–1016. DOI ↗Ashburner, J., & Friston, K. J. (2000). Voxel-based morphometry—the methods. NeuroImage, 11(6), 805–821. DOI ↗
别名NODDI, neurite density mappingVBM, grey matter morphometry
相关32
摘要Neurite Orientation Dispersion and Density Imaging (NODDI) is a biophysical diffusion MRI model that quantifies microstructural properties of white matter: neurite density (axonal density), orientation dispersion (fiber coherence), and isotropic diffusion (free water or cerebrospinal fluid). Introduced by Zhang and colleagues in 2012, NODDI provides biologically interpretable metrics directly linking diffusion MRI signals to tissue microstructure.Voxel-Based Morphometry (VBM) is a whole-brain statistical technique for detecting local differences in gray matter volume or concentration from structural MRI. Introduced by John Ashburner and Karl Friston in 2000, VBM enables researchers to identify regional brain volume changes associated with disease, aging, learning, and other factors without requiring a priori region-of-interest definitions.
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  3. PUBLISHED

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ScholarGate方法对比: NODDI · Voxel-Based Morphometry. 于 2026-06-18 检索自 https://scholargate.app/zh/compare