方法对比

	多中心病例报告	回顾性病例报告
领域	流行病学	流行病学
方法族	Process / pipeline	Process / pipeline
起源年份	Long-standing practice; CARE guidelines formalized 2013	19th century (formalized ~2013 with CARE guidelines)
提出者	Clinical medicine tradition; CARE guidelines by Gagnier et al.	Case reporting tradition in medicine (formalized by CARE guidelines, Riley et al., 2013)
类型	Observational descriptive study	Observational descriptive study
开创性文献	Gagnier, J. J., Kienle, G., Altman, D. G., Moher, D., Sox, H., & Riley, D. (2013). The CARE guidelines: Consensus-based clinical case reporting guideline development. Journal of Medical Case Reports, 7, 223.	Gagnier, J. J., Kienle, G., Altman, D. G., Moher, D., Sox, H., & Riley, D. (2013). The CARE guidelines: consensus-based clinical case reporting guideline development. Journal of Medical Case Reports, 7(1), 223.
别名	multi-site case report, collaborative case report, multicentre case report, CARE multicenter report	retrospective case study, post-hoc case report, retrospective clinical case, case report
相关	4	4
摘要	A multicenter case report is a structured clinical document describing one or a very small number of unusual patients observed across two or more independent healthcare institutions. By pooling observations from multiple sites, it overcomes the rarity barrier that prevents any single center from documenting an unusual presentation, adverse event, or novel treatment response — producing a richer, more externally valid account than a single-center report can offer.	A retrospective case report is a detailed, structured narrative of a single patient's clinical presentation, diagnosis, management, and outcome, assembled from existing medical records after the clinical events have occurred. It is the most granular and accessible observational design in clinical medicine, serving primarily to document rare presentations, unexpected outcomes, novel treatments, or unusual drug reactions that would not otherwise enter the published literature.