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| 纵向数据与生存时间联合模型× | Kaplan-Meier生存估计量× | |
|---|---|---|
| 领域 | 生存分析 | 生存分析 |
| 方法族 | Survival analysis | Survival analysis |
| 起源年份≠ | 2004 | 1958 |
| 提出者≠ | Tsiatis, A.A. & Davidian, M.; Rizopoulos, D. | Kaplan, E. L. & Meier, P. |
| 类型≠ | Semiparametric regression model | Non-parametric survival estimator |
| 开创性文献≠ | Rizopoulos, D. (2012). Joint Models for Longitudinal and Time-to-Event Data. CRC Press. DOI ↗ | Kaplan, E. L. & Meier, P. (1958). Nonparametric Estimation from Incomplete Observations. Journal of the American Statistical Association, 53(282), 457–481. DOI ↗ |
| 别名≠ | joint model, shared random effects model, longitudinal-survival joint model, Joint Model (Boylamsal + Sağkalım Birleşik Model) | product-limit estimator, km curve, kaplan-meier sağkalım analizi |
| 相关≠ | 5 | 2 |
| 摘要≠ | The joint model for longitudinal and time-to-event data, formalised by Tsiatis and Davidian in 2004 and extended comprehensively by Rizopoulos in 2012, simultaneously estimates a mixed-effects model for repeatedly measured biomarkers and a survival model for the time to an event, linking the two processes through shared random effects. It resolves two major problems that simpler approaches cannot handle: informative dropout from longitudinal studies and the endogeneity of time-varying biomarkers used as covariates in a Cox model. | The Kaplan-Meier estimator, introduced by Kaplan and Meier in 1958, is a non-parametric method that estimates the survival curve — the probability of remaining event-free over time — from right-censored time-to-event data. The log-rank test is the companion procedure used to compare survival curves between groups. |
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