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水凝胶流变学×有限元骨重塑分析(FEA Bone Remodeling)×
领域生物力学生物力学
方法族Process / pipelineProcess / pipeline
起源年份19941987
提出者Christopher MacoskoRik Huiskes
类型Mechanical material characterizationMulti-physics finite element pipeline
开创性文献Almquist, B. D., & Lu, T. W. (2002). A simple stochastic parameter estimation technique for complex models. IEEE Transactions on Biomedical Engineering, 49(10), 1188-1193. link ↗Huiskes, R., Weinans, H., Grootenboer, H. J., Dalstra, M., Fudala, B., & Slooff, T. J. (1987). Adaptive bone-remodeling theory applied to prosthetic-design analysis. Journal of Biomechanics, 20(11-12), 1135-1150. DOI ↗
别名Viscoelastic analysis, Storage modulus, Gel characterizationBone remodeling simulation, Trabecular architecture adaptation, Mechano-regulation
相关33
摘要Hydrogel rheology characterizes the mechanical viscoelastic properties of hydrogels used in tissue engineering, drug delivery, and biomedical devices. By measuring storage modulus (elastic component), loss modulus (viscous component), and their frequency dependence, practitioners assess gel stiffness, degradation, and suitability for specific applications.Finite element analysis (FEA) for bone remodeling predicts how bone tissue density and architecture adapt to changes in mechanical loading over time. Pioneered by Rik Huiskes and Donald Carter in the 1980s, this computational approach integrates stress analysis with biophysical remodeling rules to simulate the long-term response of bone to disease, aging, or surgical intervention.
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  3. PUBLISHED

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ScholarGate方法对比: Hydrogel Rheology · FEA Bone Remodeling. 于 2026-06-19 检索自 https://scholargate.app/zh/compare