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| 系统性红斑狼疮活动性医生总体评估 (PGA)× | 强直性脊柱炎疾病活动度评分 (BASDAI)× | |
|---|---|---|
| 领域 | 风湿病学 | 风湿病学 |
| 方法族 | Process / pipeline | Process / pipeline |
| 起源年份≠ | 1992 | 1994 |
| 提出者≠ | Bombardier et al. | Garrett et al. |
| 类型≠ | Clinician-rated | Patient-reported outcome (PRO) |
| 开创性文献≠ | Petri M. Thermodynamic instability in the pathogenesis of lupus nephritis. Nat Rev Rheum. 2016;12(11):635-642. link ↗ | Garrett S, Jenkinson T, Kennedy LG, Whitelock H, Gaisford P, Calin A. A new approach to defining disease status in ankylosing spondylitis: the Bath Ankylosing Spondylitis Disease Activity Index. The Journal of Rheumatology. 1994;21(12):2286-2291. link ↗ |
| 别名≠ | Physician Global Assessment, PGA-Lupus, Clinician Global Assessment-SLE | BASDAI, BAS-DAI |
| 相关≠ | 3 | 4 |
| 摘要≠ | The Physician Global Assessment (PGA) is a clinician-rated, single-item measure of overall systemic lupus erythematosus (SLE) disease activity on a visual analogue scale (0–10). Used alongside structured indices like SLEDAI, PGA captures the clinician's integrated judgment of SLE severity, synthesising clinical examination, serology, imaging, and organ-specific findings into a holistic activity score. PGA is simple, practical, and widely used in SLE research and clinical practice as a complementary measure that reflects experienced clinician assessment of disease state. | The BASDAI is a patient-reported outcome measure of disease activity in ankylosing spondylitis (AS), a chronic inflammatory arthropathy affecting the spine and axial skeleton. Introduced by Garrett et al. in 1994, BASDAI uses six simple patient self-report items focused on the cardinal symptoms of AS: fatigue, spinal pain, peripheral joint involvement, and morning stiffness. As a PRO measure, BASDAI is practical for routine monitoring, responsive to treatment, and strongly associated with clinical outcomes and spinal damage progression, making it a cornerstone outcome in AS management and clinical trials. |
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