方法对比
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| 柔性参数生存模型（Royston-Parmar）× | Cox比例风险回归× | |
|---|---|---|
| 领域 | 生存分析 | 生存分析 |
| 方法族 | Survival analysis | Survival analysis |
| 起源年份≠ | 2002 | 1972 |
| 提出者≠ | Royston, P. & Parmar, M.K.B. | Cox, D. R. |
| 类型≠ | Parametric survival regression model | Semi-parametric hazard regression model |
| 开创性文献≠ | Royston, P. & Parmar, M.K.B. (2002). Flexible Parametric Proportional-Hazards and Proportional-Odds Models for Censored Survival Data, with Application to Prognostic Modelling and Estimation of Treatment Effects. Statistics in Medicine, 21(15), 2175–2197. DOI ↗ | Cox, D. R. (1972). Regression Models and Life-Tables. Journal of the Royal Statistical Society: Series B, 34(2), 187–202. DOI ↗ |
| 别名 | flexible parametric model, restricted cubic spline survival model, stpm2, Esnek Parametrik Survival Modeli (Royston-Parmar) | cox ph model, proportional hazards model, cox ph regression, Cox Orantılı Tehlikeler Regresyonu |
| 相关≠ | 8 | 3 |
| 摘要≠ | The Royston-Parmar model, introduced by Royston and Parmar in 2002, is a modern parametric approach to survival analysis that replaces the rigid distributional assumptions of classical models with a restricted cubic spline fitted to the log-cumulative-hazard scale. It combines the interpretability of a fully parametric model with the flexibility to capture non-standard hazard shapes, and it supports proportional-hazards, accelerated failure-time, and proportional-odds link functions. | Cox proportional hazards regression, introduced by D. R. Cox in 1972, is a semi-parametric model that estimates how one or more covariates affect the hazard — the instantaneous rate of experiencing an event — while leaving the baseline hazard function unspecified. It is the standard multivariable method in survival analysis and produces hazard ratios that quantify the relative risk associated with each predictor. |
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