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有限元骨重塑分析(FEA Bone Remodeling)×微CT形态计量学×
领域生物力学生物力学
方法族Process / pipelineProcess / pipeline
起源年份19871989
提出者Rik HuiskesFeldkamp
类型Multi-physics finite element pipeline3D image acquisition and quantitative analysis
开创性文献Huiskes, R., Weinans, H., Grootenboer, H. J., Dalstra, M., Fudala, B., & Slooff, T. J. (1987). Adaptive bone-remodeling theory applied to prosthetic-design analysis. Journal of Biomechanics, 20(11-12), 1135-1150. DOI ↗Feldkamp, L. A., Davis, L. C., & Kress, J. W. (1984). Practical cone-beam algorithm. Journal of the Optical Society of America A, 1(6), 612-619. DOI ↗
别名Bone remodeling simulation, Trabecular architecture adaptation, Mechano-regulationmicroCT, Micro-CT analysis, 3D bone morphometry
相关33
摘要Finite element analysis (FEA) for bone remodeling predicts how bone tissue density and architecture adapt to changes in mechanical loading over time. Pioneered by Rik Huiskes and Donald Carter in the 1980s, this computational approach integrates stress analysis with biophysical remodeling rules to simulate the long-term response of bone to disease, aging, or surgical intervention.Micro-computed tomography (microCT) morphometry quantifies 3D bone and tissue architecture at micrometer resolution, enabling detailed assessment of bone density, trabecular structure, and porosity. Developed by Feldkamp and colleagues and standardized by the American Society for Bone and Mineral Research, microCT is the gold standard for preclinical bone analysis and has expanded to tissue engineering and material characterization.
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ScholarGate方法对比: FEA Bone Remodeling · Micro-CT Morphometry. 于 2026-06-17 检索自 https://scholargate.app/zh/compare