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析因多臂试验×多臂实验×
领域实验设计实验设计
方法族Process / pipelineProcess / pipeline
起源年份1926 (factorial basis); multi-arm factorial trials formalized 1980s–1990s1990s–2000s (clinical formalization); multi-arm concept implicit in ANOVA-era factorial designs
提出者R. A. Fisher (factorial foundations); multi-arm extension established in clinical trial methodologyDeveloped within clinical trials methodology; formalized by Parmar, Royston and colleagues (UK MRC CTU, early 2000s)
类型Experimental designExperimental design
开创性文献Montgomery, D. C. (2017). Design and Analysis of Experiments (9th ed.). Wiley. ISBN: 978-1119492443Royston, P., Parmar, M. K. B., & Qian, W. (2003). Novel designs for multi-arm clinical trials with survival outcomes with an application in ovarian cancer. Statistics in Medicine, 22(14), 2239–2256. DOI ↗
别名multi-arm factorial trial, factorial multi-arm trial, multi-arm factorial experiment, MAFTmulti-arm trial, multiple-arm experiment, multi-group experiment, many-arm design
相关65
摘要A factorial multi-arm experiment simultaneously tests multiple factors (each at two or more levels) by assigning participants to distinct arms that represent unique combinations of those factors. This design efficiently estimates the independent main effects of each factor and their interactions, all within a single study — making it far more informative than running separate one-factor experiments.A multi-arm experiment simultaneously compares three or more treatment or intervention conditions — each called an arm — against a shared control or against one another. By testing multiple alternatives in a single study, it yields more information per participant than running separate two-group experiments sequentially, while controlling the overall Type I error rate through pre-specified comparison strategies.
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ScholarGate方法对比: Factorial Multi-Arm Experiment · Multi-arm experiment. 于 2026-06-18 检索自 https://scholargate.app/zh/compare