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| 等效性检验（TOST× | 配对样本 t 检验× | |
|---|---|---|
| 领域 | 统计学 | 统计学 |
| 方法族 | Hypothesis test | Hypothesis test |
| 起源年份≠ | 1987 | 1908 |
| 提出者≠ | Donald J. Schuirmann | Student (W. S. Gosset) |
| 类型≠ | Parametric equivalence test | Parametric mean comparison (paired) |
| 开创性文献≠ | Schuirmann, D.J. (1987). A Comparison of the Two One-Sided Tests Procedure and the Power Approach for Assessing the Equivalence of Average Bioavailability. Journal of Pharmacokinetics and Biopharmaceutics, 15(6), 657–680. DOI ↗ | Field, A. (2013). Discovering Statistics Using IBM SPSS Statistics (4th ed.). SAGE. ISBN: 978-1446249185 |
| 别名 | TOST, two one-sided tests, bioequivalence test, Eşdeğerlik Testi (TOST — Two One-Sided Tests) | dependent samples t-test, repeated measures t-test, matched-pairs t-test, eşleştirilmiş örneklem t-testi |
| 相关≠ | 5 | 4 |
| 摘要≠ | The equivalence test using the Two One-Sided Tests (TOST) procedure is a parametric hypothesis test designed to demonstrate that the difference between two group means falls within a pre-specified equivalence region ±Δ. Introduced by Schuirmann (1987) in the context of pharmaceutical bioequivalence, TOST reverses the logic of classical null-hypothesis testing: instead of trying to detect a difference, it provides positive evidence of similarity. | The paired samples t-test is a parametric hypothesis test that compares two measurements taken on the same subjects — such as a before and after reading — to decide whether the average change differs from zero. It rests on the t-distribution introduced by Student (W. S. Gosset) in 1908 and works on the within-subject difference scores rather than the raw measurements. |
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