方法对比
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| 等效性检验（TOST× | 独立样本t检验× | |
|---|---|---|
| 领域 | 统计学 | 统计学 |
| 方法族 | Hypothesis test | Hypothesis test |
| 起源年份≠ | 1987 | 1908 |
| 提出者≠ | Donald J. Schuirmann | Student (W. S. Gosset) |
| 类型≠ | Parametric equivalence test | Parametric mean comparison |
| 开创性文献≠ | Schuirmann, D.J. (1987). A Comparison of the Two One-Sided Tests Procedure and the Power Approach for Assessing the Equivalence of Average Bioavailability. Journal of Pharmacokinetics and Biopharmaceutics, 15(6), 657–680. DOI ↗ | Student (1908). The probable error of a mean. Biometrika, 6(1), 1–25. DOI ↗ |
| 别名 | TOST, two one-sided tests, bioequivalence test, Eşdeğerlik Testi (TOST — Two One-Sided Tests) | student t-test, two-sample t-test, unpaired t-test, bağımsız örneklem t-testi |
| 相关≠ | 5 | 4 |
| 摘要≠ | The equivalence test using the Two One-Sided Tests (TOST) procedure is a parametric hypothesis test designed to demonstrate that the difference between two group means falls within a pre-specified equivalence region ±Δ. Introduced by Schuirmann (1987) in the context of pharmaceutical bioequivalence, TOST reverses the logic of classical null-hypothesis testing: instead of trying to detect a difference, it provides positive evidence of similarity. | The independent samples t-test is a parametric hypothesis test that compares the means of two independent groups to decide whether they differ significantly. It builds on the t-distribution introduced by Student (W. S. Gosset) in 1908 and assumes the measured values are continuous, approximately normally distributed, and have equal variances. |
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