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生态学研究×剂量-反应分析×
领域流行病学流行病学
方法族Process / pipelineProcess / pipeline
起源年份19th century (Snow 1854); formalised mid-20th centuryConceptual roots 16th century; modern epidemiological application mid-20th century
提出者Various; foundational work by John Snow (1854) and systematised in modern form by Brian MacMahon and colleaguesParacelsus (conceptual foundation); formalized by John Snow and later Bradford Hill
类型Observational epidemiological studyQuantitative analytical method
开创性文献Morgenstern, H. (1995). Ecologic studies in epidemiology: concepts, principles, and methods. Annual Review of Public Health, 16(1), 61–81. DOI ↗Rothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755641
别名aggregate study, correlational study, ecological correlation study, population-level studyexposure-response analysis, concentration-response modeling, dose-response modeling, DRA
相关54
摘要An ecological study is an observational epidemiological design in which the unit of analysis is a group or population — a country, region, city, or time period — rather than an individual. Exposures and outcomes are measured as aggregates (rates, proportions, or means) and then correlated across groups to generate or evaluate hypotheses about population-level associations between risk factors and disease.Dose-response analysis quantifies the relationship between the magnitude of an exposure (the dose) and the probability or rate of an outcome (the response). It is a core analytical strategy in epidemiology and toxicology, providing evidence that increasing exposure systematically increases — or decreases — the risk of disease. A demonstrated dose-response gradient is one of Bradford Hill's classic criteria supporting causal inference.
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ScholarGate方法对比: Ecological Study · Dose-Response Analysis. 于 2026-06-17 检索自 https://scholargate.app/zh/compare