方法对比

	双盲单被试实验设计	多基线设计
领域	实验设计	实验设计
方法族	Process / pipeline	Process / pipeline
起源年份	1970s–1980s (systematic integration of blinding into SCED)	1968
提出者	Barlow, Hersen, and colleagues (single-subject tradition); double-blind masking adapted from clinical trial methodology	Donald M. Baer, Montrose M. Wolf, Todd R. Risley
类型	Experimental single-subject design with double-blind masking	Single-subject experimental design
开创性文献	Kazdin, A. E. (2011). Single-Case Research Designs: Methods for Clinical and Applied Settings (2nd ed.). Oxford University Press. ISBN: 978-0195341881	Baer, D. M., Wolf, M. M., & Risley, T. R. (1968). Some current dimensions of applied behavior analysis. Journal of Applied Behavior Analysis, 1(1), 91–97.
别名	double-blind SCED, double-blind single-case experimental design, masked single-subject design, double-blind N-of-1 design	MBD, multiple-baseline single-case design, staggered baseline design, multiple-probe design
相关	5	4
摘要	A double-blind single-subject experimental design applies systematic masking — concealing treatment assignment from both the participant and the outcome assessor — within a within-person repeated-measures framework. It is used when researchers need strong causal inference about an intervention's effect on a single individual while guarding against placebo responses and observer bias. Particularly prominent in pharmacological, behavioral, and clinical rehabilitation research.	The multiple baseline design is a single-subject experimental design that demonstrates functional control by introducing an intervention at staggered time points across two or more baselines — typically across different behaviors, individuals, or settings. Because no withdrawal of treatment is required, it is especially suitable when the target behavior is irreversible or when removing an effective intervention would be unethical.