方法对比

	双盲单被试实验设计	ABAB设计
领域	实验设计	实验设计
方法族	Process / pipeline	Process / pipeline
起源年份	1970s–1980s (systematic integration of blinding into SCED)	1960s (Sidman 1960; Baer et al. 1968)
提出者	Barlow, Hersen, and colleagues (single-subject tradition); double-blind masking adapted from clinical trial methodology	Murray Sidman; Baer, Wolf & Risley (applied behavior analysis formalization)
类型	Experimental single-subject design with double-blind masking	Single-subject experimental design
开创性文献	Kazdin, A. E. (2011). Single-Case Research Designs: Methods for Clinical and Applied Settings (2nd ed.). Oxford University Press. ISBN: 978-0195341881	Sidman, M. (1960). Tactics of Scientific Research: Evaluating Experimental Data in Psychology. Basic Books.
别名	double-blind SCED, double-blind single-case experimental design, masked single-subject design, double-blind N-of-1 design	reversal design, withdrawal design, ABAB reversal, operant reversal design
相关	5	4
摘要	A double-blind single-subject experimental design applies systematic masking — concealing treatment assignment from both the participant and the outcome assessor — within a within-person repeated-measures framework. It is used when researchers need strong causal inference about an intervention's effect on a single individual while guarding against placebo responses and observer bias. Particularly prominent in pharmacological, behavioral, and clinical rehabilitation research.	The ABAB design is a single-subject experimental methodology that establishes causal control by repeatedly introducing and removing an intervention. A baseline phase (A) is followed by an intervention phase (B), then a return to baseline (A), and a second intervention phase (B), allowing the researcher to demonstrate that observed behavior changes are produced by the intervention rather than by coincidental factors.