方法对比
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| 双盲实验室实验× | 随机对照试验 (RCT)× | |
|---|---|---|
| 领域 | 实验设计 | 实验设计 |
| 方法族≠ | Process / pipeline | Hypothesis test |
| 起源年份≠ | Mid-20th century (widespread adoption ~1950s onward) | 1948 |
| 提出者≠ | Rooted in 19th-century pharmacological and psychological research traditions; systematized in clinical and experimental science through the 20th century | James Lind (early precursor, 1747); modern formulation: Austin Bradford Hill & Medical Research Council (1948) |
| 类型≠ | Controlled experimental design with blinding | Interventional comparative study |
| 开创性文献≠ | Shadish, W. R., Cook, T. D., & Campbell, D. T. (2002). Experimental and Quasi-Experimental Designs for Generalized Causal Inference. Houghton Mifflin. ISBN: 978-0395615560 | Schulz, K.F., Altman, D.G., Moher, D., for the CONSORT Group (2010). CONSORT 2010 Statement: Updated Guidelines for Reporting Parallel Group Randomised Trials. BMJ, 340, c332. DOI ↗ |
| 别名 | double-blind lab experiment, double-masked laboratory experiment, DB lab experiment, double-blind controlled lab study | RCT, randomised controlled trial, clinical trial, Randomize Kontrollü Çalışma (RCT) Tasarımı |
| 相关≠ | 5 | 7 |
| 摘要≠ | A double-blind laboratory experiment is a controlled experimental design conducted in a laboratory setting in which neither the participants nor the researchers directly administering the treatment know which condition each participant has been assigned to. This dual blinding, combined with the high degree of environmental control characteristic of laboratory settings, minimizes both participant expectancy effects and experimenter bias, making it one of the most rigorous designs available for isolating causal relationships between independent and dependent variables. | A randomized controlled trial (RCT) is the gold standard experimental design in clinical and health research, in which participants are randomly allocated to a treatment group or a control group so that the effect of an intervention can be measured with the highest possible degree of internal validity. The modern parallel-group RCT was formalized by Austin Bradford Hill and the Medical Research Council in their landmark streptomycin trial of 1948, and its reporting is governed today by the CONSORT 2010 guidelines (Schulz et al., 2010). |
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