方法对比
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| 循环伏安法× | 表面等离激元共振× | |
|---|---|---|
| 领域 | 光谱学 | 光谱学 |
| 方法族 | Process / pipeline | Process / pipeline |
| 起源年份≠ | 1964 | 1971 |
| 提出者≠ | Randles Semyon Nicholson | Erich Kretschmann |
| 类型≠ | Electrochemical technique | Optical technique |
| 开创性文献≠ | Nicholson, R. S., & Shain, I. (1964). Electroanalytical chemistry. Analytical Chemistry, 36(4), 706-723. link ↗ | Kretschmann, E. (1971). Determination of optical constants of metals by excitation of surface plasmons. Zeitschrift für Physik, 241(4), 313-324. link ↗ |
| 别名 | CV, cyclic voltammetry, electrochemistry | SPR, surface plasmon, SPR biosensing |
| 相关 | 3 | 3 |
| 摘要≠ | Cyclic Voltammetry (CV) is an electrochemical technique that measures redox reactions by varying the voltage applied to an electrode and monitoring the resulting current. Developed by Nicholson and Shain in 1964, CV is one of the most widely used electrochemical methods, providing rapid information about the redox potentials and electron-transfer kinetics of molecules and materials. | Surface Plasmon Resonance (SPR) is a real-time, label-free technique for detecting and monitoring biomolecular interactions at a sensor surface by measuring changes in the refractive index caused by ligand binding. Developed by Kretschmann in 1971 and applied to biosensing by Liedberg, Nylander, and Lundström in 1983, SPR is now a gold standard for measuring binding kinetics (association and dissociation rates) and equilibrium binding constants in protein interactions, antibody-antigen recognition, and drug discovery. |
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