方法对比
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| 交叉对照组实验设计× | 交叉析因实验× | |
|---|---|---|
| 领域 | 实验设计 | 实验设计 |
| 方法族 | Process / pipeline | Process / pipeline |
| 起源年份≠ | Mid-20th century; systematic treatment from 1980s onward | 1920s–1960s (synthesis of factorial and crossover traditions) |
| 提出者≠ | Established in clinical pharmacology and agricultural research; formalized by B. Jones & M. G. Kenward | R. A. Fisher (factorial principles, 1920s); crossover integration developed in biostatistics through mid-20th century |
| 类型 | Experimental design | Experimental design |
| 开创性文献≠ | Jones, B., & Kenward, M. G. (2003). Design and Analysis of Cross-Over Trials (2nd ed.). Chapman and Hall/CRC. ISBN: 978-1584883500 | Jones, B., & Kenward, M. G. (2014). Design and Analysis of Cross-Over Trials (3rd ed.). Chapman and Hall/CRC. ISBN: 978-1439861424 |
| 别名 | crossover controlled trial, within-subject crossover with control, AB/BA crossover controlled design, repeated-measures crossover with control arm | within-subject factorial design, repeated-measures factorial experiment, factorial crossover trial, crossover factorial trial |
| 相关≠ | 6 | 5 |
| 摘要≠ | A crossover control group experimental design is an experimental approach in which participants are randomly assigned to sequences of conditions that include both a treatment and a control (no-treatment or placebo) period, with each participant experiencing both the experimental and control conditions in succession. By using each participant as their own control across periods, this design sharply reduces between-subject variability and typically requires fewer participants than parallel group trials to achieve equivalent statistical power. | A crossover factorial experiment combines two powerful design principles: factorial structure, which studies multiple factors and their interactions simultaneously, and crossover structure, in which each participant receives more than one treatment combination across sequential periods. By serving as their own control, participants reduce between-subject variability, improving statistical power while also revealing how different factor levels interact within the same individual. |
| ScholarGate数据集 ↗ |
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