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横断面流行病学研究×随机对照试验 (RCT)×
领域流行病学流行病学
方法族Process / pipelineProcess / pipeline
起源年份1960s (formal codification); widely practiced since mid-20th century1948 (first rigorously conducted RCT — MRC streptomycin trial)
提出者Classical epidemiology tradition; systematized by Brian MacMahon and Thomas Pugh (1960s)Austin Bradford Hill; MRC Streptomycin Trial team
类型Observational, descriptive/analytic epidemiological designInterventional experimental study
开创性文献Kelsey, J. L., Whittemore, A. S., Evans, A. S., & Thompson, W. D. (1996). Methods in Observational Epidemiology (2nd ed.). Oxford University Press. ISBN: 978-0195080407Friedman, L. M., Furberg, C. D., DeMets, D. L., Reboussin, D. M., & Granger, C. B. (2015). Fundamentals of Clinical Trials (5th ed.). Springer. ISBN: 978-3319185385
别名prevalence study, cross-sectional survey, transversal study, cross-sectional designRCT, randomized controlled trial, randomised controlled trial, clinical randomized trial
相关66
摘要A cross-sectional epidemiological study measures the exposure(s) and outcome(s) of interest simultaneously in a defined population at a single point in time (or over a short period). Because there is no follow-up, it is the most efficient observational design for estimating disease prevalence and for generating hypotheses about associations between risk factors and health outcomes.A randomized clinical trial (RCT) is an experimental study design in which participants are randomly assigned to an intervention group or a control group, then followed prospectively to compare outcomes. Random allocation is the defining feature: it distributes known and unknown confounders across groups by chance, making the RCT the strongest individual study design for establishing causal efficacy of a treatment or intervention under controlled conditions.
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ScholarGate方法对比: Cross-sectional epidemiological study · Randomized clinical trial. 于 2026-06-19 检索自 https://scholargate.app/zh/compare