方法对比

	哥伦比亚自杀严重程度评定量表 (C-SSRS)	患者总体改善印象 (PGIC)
领域	临床心理学	临床心理学
方法族	Process / pipeline	Process / pipeline
起源年份	2008	1976
提出者	Kelly Posner	William Guy
类型	Clinician-administered interview scale	Self-report single-item rating
开创性文献	Posner, K., Brown, G. K., Stanley, B., Brent, D. A., Yershova, K. V., Oquendo, M. A., & Shen, S. (2011). The Columbia-Suicide Severity Rating Scale: initial validity and internal consistency findings from three multisite studies with adolescents and adults. American Journal of Psychiatry, 168(12), 1266–1277.	Guy, W. (1976). ECDEU Assessment Manual for Psychopharmacology. Rockville, MD: National Institute of Mental Health, US Department of Health, Education, and Welfare.
别名	C-SSRS, Columbia Suicide Severity Rating Scale	PGIC, Patient Global Impression of Change Scale
相关	4	4
摘要	The Columbia-Suicide Severity Rating Scale is a brief clinician-administered assessment of suicide risk developed by Kelly Posner and colleagues at Columbia University to address limitations in prior screening tools. First published in the American Journal of Psychiatry in 2011, the C-SSRS has become the FDA-endorsed standard for monitoring suicidal ideation and behavior in antidepressant, anticonvulsant, and neuropsychiatric medication trials. The scale assesses both suicidal ideation (frequency and intensity) and suicidal behavior (attempts, preparatory acts) over defined time windows, providing structured risk stratification.	The Patient Global Impression of Change is a single-item, seven-point rating scale asking patients to report their overall impression of change since treatment initiation. Originally published by William Guy in the ECDEU Assessment Manual in 1976, the PGIC has become a standard co-primary endpoint in clinical trials assessing treatment efficacy. The scale is endorsed by the FDA as a patient-reported outcome measure for demonstrating clinical benefit. Despite its simplicity, the PGIC captures patients' holistic perception of improvement—integrating symptom reduction, functional recovery, and subjective well-being.