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簇随机对照试验设计×析因随机对照试验×
领域实验设计实验设计
方法族Process / pipelineProcess / pipeline
起源年份1990s (formal methodology development)1926 (Fisher factorial foundations); 2000s–2010s (clinical factorial RCT formalization)
提出者Murray, D. M.; Donner, A. and Klar, N. (systematic formalization)R. A. Fisher (factorial design foundations); adapted into clinical trials via MOST framework (Collins et al., 2014)
类型Experimental designExperimental trial design
开创性文献Donner, A., & Klar, N. (2000). Design and Analysis of Cluster Randomization Trials in Health Research. Arnold. ISBN: 978-0340691533Collins, L. M., Dziak, J. J., Kugler, K. C., & Trail, J. B. (2014). Factorial experiments: Efficient tools for evaluation of intervention components. American Journal of Preventive Medicine, 47(4), 498–504. DOI ↗
别名CRCT with control group, group-randomized trial, cluster RCT control group design, community randomized controlled trialFactorial RCT, factorial trial, multi-factor RCT, factorial experiment with randomization
相关66
摘要A cluster randomized control group experimental design randomly assigns intact groups (clusters) — such as schools, clinics, or communities — rather than individuals to treatment or control conditions. At least one cluster group receives no active intervention, serving as the control. This design is essential when individual randomization is impractical or contamination between participants in close proximity is likely.A factorial randomized controlled trial (factorial RCT) is an experimental design in which participants are randomly assigned to every possible combination of two or more independent factors (treatments or intervention components) simultaneously. This allows researchers to estimate the main effect of each factor and their interactions within a single, efficient trial, rather than running separate experiments for each factor.
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ScholarGate方法对比: Cluster Randomized Control Group Experimental Design · Factorial Randomized Controlled Trial. 于 2026-06-18 检索自 https://scholargate.app/zh/compare