方法对比
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| 簇随机对照试验设计× | 分块随机对照试验× | |
|---|---|---|
| 领域 | 实验设计 | 实验设计 |
| 方法族 | Process / pipeline | Process / pipeline |
| 起源年份≠ | 1990s (formal methodology development) | 1920s (Fisher's blocking principle); applied to RCTs from the 1940s onward |
| 提出者≠ | Murray, D. M.; Donner, A. and Klar, N. (systematic formalization) | R. A. Fisher (blocking principle); systematic RCT application by Bradford Hill and later Pocock, Friedman et al. |
| 类型 | Experimental design | Experimental design |
| 开创性文献≠ | Donner, A., & Klar, N. (2000). Design and Analysis of Cluster Randomization Trials in Health Research. Arnold. ISBN: 978-0340691533 | Friedman, L. M., Furberg, C. D., DeMets, D. L., Reboussin, D. M., & Granger, C. B. (2010). Fundamentals of Clinical Trials (4th ed.). Springer. ISBN: 978-1441915856 |
| 别名 | CRCT with control group, group-randomized trial, cluster RCT control group design, community randomized controlled trial | blocked RCT, block-randomized trial, stratified block randomization trial, permuted block randomization |
| 相关≠ | 6 | 5 |
| 摘要≠ | A cluster randomized control group experimental design randomly assigns intact groups (clusters) — such as schools, clinics, or communities — rather than individuals to treatment or control conditions. At least one cluster group receives no active intervention, serving as the control. This design is essential when individual randomization is impractical or contamination between participants in close proximity is likely. | A blocked randomized controlled trial (blocked RCT) uses permuted-block randomization to ensure that treatment groups remain balanced in size — and optionally in key characteristics — throughout recruitment. Within each block of fixed or randomly varied size, all treatment allocations are present in equal numbers, so imbalance cannot accumulate even if the trial is stopped early. This makes blocked RCTs the standard randomization approach in clinical and behavioral intervention research. |
| ScholarGate数据集 ↗ |
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