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| 肝硬化Child-Pugh评分× | 肝性脑病韦斯特黑文标准× | |
|---|---|---|
| 领域 | 胃肠病学 | 胃肠病学 |
| 方法族 | Process / pipeline | Process / pipeline |
| 起源年份≠ | 1964 (Child-Turcotte), 1973 (Pugh modification) | 1966 (original), 1978 (formalized) |
| 提出者≠ | Child, C. G., Turcotte, J. G., and Pugh, R. N. | West Haven Group (Parsons, Williams, Sherlock, Trey, Davidson) |
| 类型 | Clinician-rated | Clinician-rated |
| 开创性文献≠ | Child, C. G., & Turcotte, J. G. (1964). Surgery and portal hypertension. In C. G. Child (Ed.), The liver and portal hypertension (pp. 50–64). Saunders. link ↗ | Parsons, P. L., Williams, R., & Sherlock, S. (1978). The role of plasma amino acids in hepatic encephalopathy and the effect of branched-chain amino acid infusion. Gut, 19(10), 969–978. link ↗ |
| 别名≠ | Child-Turcotte-Pugh Score, CTP Score | Hepatic Encephalopathy Grading, HE Grade, West Haven Grade |
| 相关 | 4 | 4 |
| 摘要≠ | The Child-Pugh Score (originally Child-Turcotte, modified by Pugh in 1973) is a clinical scoring system that stratifies the severity of liver cirrhosis and predicts surgical mortality and prognosis. The score integrates five readily available clinical and laboratory parameters: bilirubin, albumin, prothrombin time (INR), ascites, and hepatic encephalopathy. With a total range of 5–15 points, the Child-Pugh Score is stratified into Class A (mild, 5–6 points), Class B (moderate, 7–9 points), and Class C (severe, 10–15 points), each with distinct mortality predictions. | The West Haven Criteria are the standard for grading hepatic encephalopathy (HE) severity, ranging from subclinical (Grade 0) to deep coma (Grade 4). Developed by Trey and Davidson in the 1960s and refined by the West Haven group, these criteria integrate mental status changes (confusion, asterixis, disorientation) and consciousness level to stage HE. The West Haven grade is a strong predictor of short-term prognosis in cirrhosis and guides urgency of intervention (lactulose, rifaxomicin, mannitol, intubation). |
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