方法对比

	贝叶斯Box-Behnken设计	中心复合设计
领域	实验设计	实验设计
方法族	Process / pipeline	Process / pipeline
起源年份	1960 (BBD); Bayesian integration ~1990s–2000s	1951
提出者	Box & Behnken (classical BBD, 1960); Bayesian extension developed by multiple authors in response surface literature	George E. P. Box and K. B. Wilson
类型	Bayesian response surface experimental design	Response surface experimental design
开创性文献	Box, G. E. P., & Behnken, D. W. (1960). Some new three level designs for the study of quantitative variables. Technometrics, 2(4), 455–475.	Box, G. E. P., & Wilson, K. B. (1951). On the experimental attainment of optimum conditions. Journal of the Royal Statistical Society: Series B, 13(1), 1–45.
别名	Bayesian BBD, Bayesian RSM Box-Behnken, Bayesian three-level design, BBD with Bayesian optimization	CCD, Box-Wilson design, central composite response surface design, rotatable central composite design
相关	5	3
摘要	Bayesian Box-Behnken Design combines the classical Box-Behnken three-level design structure with Bayesian statistical inference to fit and optimize response surface models. It uses mid-edge and center points to efficiently estimate a second-order polynomial response surface while incorporating prior knowledge about model parameters and propagating uncertainty through to predictions and optimal factor settings. The approach is widely applied in engineering process optimization and formulation studies.	Central Composite Design (CCD) is a second-order response surface design that allows researchers to efficiently fit a full quadratic model relating multiple continuous input factors to one or more response variables. Introduced by Box and Wilson in 1951, it combines a factorial (or fractional factorial) core, axial (star) points, and center-point replicates into a single unified design, making it the most widely used design for process optimization in engineering, chemistry, and manufacturing.