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肌萎缩侧索硬化功能评定量表修订版 (ALSFRS-R)×多发性硬化步行量表-12 (MSWS-12)×
领域神经病学神经病学
方法族Process / pipelineProcess / pipeline
起源年份19992003
提出者James M. Cedarbaum, NIH/NINDSJeremy C. Hobart, University of Plymouth
类型Clinician-rated and patient-reported hybridSelf-report questionnaire
开创性文献Cedarbaum, J. M., Stambler, N., Malta, E., Fuller, C., Hilt, D., Thurmond, B., & Nakanishi, A. (1999). The ALSFRS-R: A revised ALS functional rating scale that incorporates assessments of respiratory function. Journal of the Neurological Sciences, 169(1-2), 13-21. DOI ↗Hobart, J. C., Riazi, A., Lamping, D. L., Fitzpatrick, R., & Thompson, A. J. (2003). Measuring the impact of MS on walking ability: The 12-Item MS Walking Scale (MSWS-12). Neurology, 60(1), 31-36. DOI ↗
别名ALS FRS-R, Amyotrophic Lateral Sclerosis Functional Rating Scale-RevisedMS Walking Scale-12, MSWS
相关43
摘要The ALSFRS-R is a 12-item clinician-administered functional rating scale designed to assess disease progression and functional status in amyotrophic lateral sclerosis (ALS). Introduced by Cedarbaum and colleagues in 1999, it expands upon the original ALSFRS by incorporating respiratory function assessment. It is the primary outcome measure in ALS clinical trials and routine clinical monitoring, providing quantitative tracking of disease decline that predicts survival and guides management decisions.The MSWS-12 is a brief, patient-reported outcome measure specifically designed to assess the impact of multiple sclerosis on walking ability and limitation. Developed by Hobart and colleagues in 2003, this 12-item scale captures both the physical difficulty and functional consequences of MS-related gait impairment. It is highly responsive to change and widely used in MS clinical trials and practice as a primary outcome measure for assessing intervention effects on mobility.
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ScholarGate方法对比: ALSFRS-R · MSWS-12. 于 2026-06-18 检索自 https://scholargate.app/zh/compare