方法对比

	Addenbrooke's认知检查	迷你精神状态检查
领域	神经心理学	神经心理学
方法族	Process / pipeline	Process / pipeline
起源年份	2000	1975
提出者	Padasalai Mathuranath	Marshall Folstein
类型	Clinician-administered comprehensive cognitive examination	Clinician-administered cognitive screening instrument
开创性文献	Mathuranath, P. S., Nestor, P. J., Berrios, G. E., Rakowicz, W., & Hodges, J. R. (2000). A brief cognitive test battery to differentiate Alzheimer's disease and frontotemporal dementia. Neurology, 55(11), 1613-1620.	Folstein, M. F., Folstein, S. E., & McHugh, P. R. (1975). Mini-mental state: A practical method for grading the cognitive state of patients for the clinician. Journal of Psychiatric Research, 12(3), 189-198.
别名	ACE, ACE-R, ACE-III, Addenbrooke Cognitive Examination	MMSE, Folstein MMSE
相关	5	5
摘要	The Addenbrooke's Cognitive Examination (ACE) is a brief yet comprehensive clinician-administered cognitive battery designed to assess multiple cognitive domains and differentiate between types of dementia. Originally developed by Mathuranath and colleagues at Cambridge University in 2000, the ACE was created to address limitations of single-domain screening tools. The revised version (ACE-R, 2006) and further refined version (ACE-III, 2013) provide updated norms and improved sensitivity. The ACE-R and ACE-III are particularly valuable for distinguishing Alzheimer's disease from frontotemporal dementia.	The Mini-Mental State Examination (MMSE) is a brief, 30-point screening instrument developed by Folstein, Folstein, and McHugh in 1975 to assess cognitive function in clinical settings. It is designed to detect cognitive impairment and monitor cognitive decline over time, particularly in older adults and patients with suspected dementia. The MMSE remains one of the most widely used cognitive screening tools in primary care, neurology, and geriatric medicine worldwide.