方法对比

	阿尔茨海默病评估量表-认知功能部分	Mattis失智症評估量表
领域	神经心理学	神经心理学
方法族	Process / pipeline	Process / pipeline
起源年份	1984	1988
提出者	William Rosen	Sandra Mattis
类型	Clinician-administered cognitive scale for Alzheimer's disease	Clinician-administered comprehensive neuropsychological scale
开创性文献	Rosen, W. G., Mohs, R. C., & Davis, K. L. (1984). A new rating scale for Alzheimer's disease. American Journal of Psychiatry, 141(11), 1356-1364.	Mattis, S. (1988). Dementia Rating Scale (DRS). Odessa, FL: Psychological Assessment Resources.
别名	ADAS-Cog, ADAS-Cog14, ADAS-Cog13	DRS, Mattis DRS, Dementia Rating Scale
相关	5	5
摘要	The Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog) is a clinician-administered cognitive assessment instrument designed specifically to measure cognitive decline in Alzheimer's disease. Developed by Rosen, Mohs, and Davis in 1984 and published in the American Journal of Psychiatry, the ADAS-Cog has become the gold standard outcome measure in pharmaceutical trials of antidementia drugs. It is sensitive to disease progression and capable of detecting cognitive change over periods as brief as 6–12 months.	The Mattis Dementia Rating Scale (DRS) is a comprehensive 36-item clinician-administered neuropsychological battery designed to assess and quantify cognitive decline in dementia. Developed by Sandra Mattis in 1988, the DRS measures five major cognitive domains—attention, initiation/perseveration, construction, conceptualization, and memory—and provides both a total score and subscale scores. The DRS is particularly valued in neurodegenerative disease research and clinical settings for its sensitivity to cognitive change over time and its utility in detecting cognitive impairment across the dementia spectrum.