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阿尔茨海默病评估量表-认知功能部分×Addenbrooke's认知检查×
领域神经心理学神经心理学
方法族Process / pipelineProcess / pipeline
起源年份19842000
提出者William RosenPadasalai Mathuranath
类型Clinician-administered cognitive scale for Alzheimer's diseaseClinician-administered comprehensive cognitive examination
开创性文献Rosen, W. G., Mohs, R. C., & Davis, K. L. (1984). A new rating scale for Alzheimer's disease. American Journal of Psychiatry, 141(11), 1356-1364. DOI ↗Mathuranath, P. S., Nestor, P. J., Berrios, G. E., Rakowicz, W., & Hodges, J. R. (2000). A brief cognitive test battery to differentiate Alzheimer's disease and frontotemporal dementia. Neurology, 55(11), 1613-1620. DOI ↗
别名ADAS-Cog, ADAS-Cog14, ADAS-Cog13ACE, ACE-R, ACE-III, Addenbrooke Cognitive Examination
相关55
摘要The Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog) is a clinician-administered cognitive assessment instrument designed specifically to measure cognitive decline in Alzheimer's disease. Developed by Rosen, Mohs, and Davis in 1984 and published in the American Journal of Psychiatry, the ADAS-Cog has become the gold standard outcome measure in pharmaceutical trials of antidementia drugs. It is sensitive to disease progression and capable of detecting cognitive change over periods as brief as 6–12 months.The Addenbrooke's Cognitive Examination (ACE) is a brief yet comprehensive clinician-administered cognitive battery designed to assess multiple cognitive domains and differentiate between types of dementia. Originally developed by Mathuranath and colleagues at Cambridge University in 2000, the ACE was created to address limitations of single-domain screening tools. The revised version (ACE-R, 2006) and further refined version (ACE-III, 2013) provide updated norms and improved sensitivity. The ACE-R and ACE-III are particularly valuable for distinguishing Alzheimer's disease from frontotemporal dementia.
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ScholarGate方法对比: Alzheimer's Disease Assessment Scale-Cognitive · Addenbrooke's Cognitive Examination. 于 2026-06-19 检索自 https://scholargate.app/zh/compare