Process / pipelineSimulation / optimization
Bayesian Markov Model — State-Transition Modeling with Bayesian Parameter Estimation
A Bayesian Markov model is a state-transition simulation method that combines Markov chain cohort modeling with Bayesian statistical inference. By placing prior distributions on transition probabilities and updating them with observed data, the approach propagates full parameter uncertainty through the simulation, yielding posterior distributions over outcomes such as costs, life-years, or quality-adjusted life-years rather than single-point estimates.
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Sources
- Briggs, A., Sculpher, M., Claxton, K. (2006). Decision Modelling for Health Economic Evaluation. Oxford University Press, Oxford. ISBN: 9780198526629
- Jackson, C. H., Sharples, L. D., Thompson, S. G. (2010). Structural and parameter uncertainty in Bayesian cost-effectiveness models. Journal of the Royal Statistical Society: Series C (Applied Statistics), 59(2), 233-253. DOI: 10.1111/j.1467-9876.2009.00684.x ↗