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Systemic Lupus Erythematosus Disease Activity Index×Bath Ankylosing Spondylitis Disease Activity Index (BASDAI)×คะแนนกิจกรรมโรคข้อ 28 ข้อ (DAS28)×
สาขาวิชาวิทยาโรคข้อวิทยาโรคข้อวิทยาโรคข้อ
ตระกูลProcess / pipelineProcess / pipelineProcess / pipeline
ปีกำเนิด200219941995
ผู้ริเริ่มGladman et al.Garrett et al.Prevoo et al.
ประเภทClinician-ratedPatient-reported outcome (PRO)Clinician-rated
แหล่งต้นตำรับGladman DD, Ibañez D, Urowitz MB. Systemic Lupus Erythematosus Disease Activity Index 2000. The Journal of Rheumatology. 2002;29(2):288-291. link ↗Garrett S, Jenkinson T, Kennedy LG, Whitelock H, Gaisford P, Calin A. A new approach to defining disease status in ankylosing spondylitis: the Bath Ankylosing Spondylitis Disease Activity Index. The Journal of Rheumatology. 1994;21(12):2286-2291. link ↗Prevoo ML, Hart's AM, Van Houwelingen HC, et al. Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis & Rheumatism. 1995;38(1):44-48. DOI ↗
ชื่อเรียกอื่นSLEDAI, SLEDAI-2K, SLE Disease Activity IndexBASDAI, BAS-DAIDAS28, DAS28-CRP, DAS28-ESR
ที่เกี่ยวข้อง343
สรุปThe SLEDAI is a comprehensive clinician-assessed measure of systemic lupus erythematosus (SLE) disease activity, capturing manifestations across multiple organ systems (cutaneous, renal, neuropsychiatric, hematologic, and serological). Introduced by Bombardier et al. (1992) and refined as SLEDAI-2K by Gladman et al. (2002), SLEDAI uses weighted scoring of 24 clinical and laboratory features to quantify overall SLE activity. It is the most widely used outcome measure in SLE research and clinical trials, enabling standardised assessment of disease progression, flare prediction, and treatment response in this complex multisystem disease.The BASDAI is a patient-reported outcome measure of disease activity in ankylosing spondylitis (AS), a chronic inflammatory arthropathy affecting the spine and axial skeleton. Introduced by Garrett et al. in 1994, BASDAI uses six simple patient self-report items focused on the cardinal symptoms of AS: fatigue, spinal pain, peripheral joint involvement, and morning stiffness. As a PRO measure, BASDAI is practical for routine monitoring, responsive to treatment, and strongly associated with clinical outcomes and spinal damage progression, making it a cornerstone outcome in AS management and clinical trials.The DAS28 is a composite measure of rheumatoid arthritis (RA) disease activity, combining joint counts, inflammatory markers, and patient-reported global health. Developed in 1995 by Prevoo and colleagues, it has become the gold standard for monitoring RA activity in clinical trials and practice. It integrates objective clinical signs with laboratory and subjective assessment, providing a single numerical index of disease burden.
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ScholarGateเปรียบเทียบวิธี: Systemic Lupus Erythematosus Disease Activity Index · Bath Ankylosing Spondylitis Disease Activity Index · Disease Activity Score 28. สืบค้นเมื่อ 2026-06-18 จาก https://scholargate.app/th/compare