เปรียบเทียบวิธี

	การทดลองในห้องปฏิบัติการแบบปกปิดฝ่ายเดียว	การทดลองสุ่มและมีกลุ่มควบคุมแบบปกปิดฝ่ายเดียว
สาขาวิชา	การออกแบบการทดลอง	การออกแบบการทดลอง
ตระกูล	Process / pipeline	Process / pipeline
ปีกำเนิด	Late 19th century; codified in 20th-century clinical and behavioral research	1948 (formalized); single-blind variant established in mid-20th century clinical trial methodology
ผู้ริเริ่ม	Formalized in experimental psychology and pharmacology; Peirce & Jastrow (1884) early instance	Bradford Hill and colleagues (MRC streptomycin trial, 1948); blinding conventions codified in CONSORT guidelines
ประเภท	Controlled experimental design	Experimental design — blinded randomized trial
แหล่งต้นตำรับ	Shadish, W. R., Cook, T. D., & Campbell, D. T. (2002). Experimental and Quasi-Experimental Designs for Generalized Causal Inference. Houghton Mifflin. ISBN: 978-0395615560	Schulz, K. F., Altman, D. G., Moher, D., & CONSORT Group. (2010). CONSORT 2010 statement: Updated guidelines for reporting parallel group randomised trials. BMJ, 340, c332.
ชื่อเรียกอื่น	single-masked laboratory study, participant-blind lab experiment, single-blind controlled lab study	single-masked RCT, single-blind RCT, single-blind trial, SB-RCT
ที่เกี่ยวข้อง	5	5
สรุป	A single-blind laboratory experiment is a controlled study conducted in a laboratory setting in which participants do not know which condition (e.g., treatment or control) they have been assigned to, while the researchers administering the conditions are aware. This masking of participants reduces demand characteristics and response bias without requiring full investigator blinding, and the controlled laboratory environment allows tight manipulation of independent variables and precise measurement of outcomes.	A single-blind randomized controlled trial (SB-RCT) is a rigorous experimental design in which participants are randomly assigned to treatment or control conditions while remaining unaware of which condition they have received. Investigators, outcome assessors, and data analysts are not blinded. By masking participants, the design eliminates placebo and nocebo response biases on the participant side, while preserving investigator flexibility to administer and monitor the intervention.