เปรียบเทียบวิธี

	การออกแบบการทดลองโดยใช้การจำลองช่วย (Simulation-Assisted Design of Experiments)	การออกแบบการทดลอง
สาขาวิชา	การออกแบบการทดลอง	การออกแบบการทดลอง
ตระกูล	Process / pipeline	Process / pipeline
ปีกำเนิด	1970s–1990s (formalized with computer experimentation growth)	1935
ผู้ริเริ่ม	Multiple contributors; systematized by Jack P.C. Kleijnen and Thomas J. Santner et al.	Ronald A. Fisher
ประเภท	Hybrid experimental-computational method	Experimental planning framework
แหล่งต้นตำรับ	Santner, T. J., Williams, B. J., & Notz, W. I. (2003). The Design and Analysis of Computer Experiments. Springer. ISBN: 978-0387954202	Fisher, R. A. (1935). The Design of Experiments. Oliver and Boyd.
ชื่อเรียกอื่น	Simulation-based DoE, Virtual DoE, Computer-aided DoE, SA-DoE	DOE, experimental design, factorial experimentation, planned experimentation
ที่เกี่ยวข้อง	5	3
สรุป	Simulation-assisted design of experiments (SA-DoE) integrates computational simulation tools — such as finite element analysis (FEA), computational fluid dynamics (CFD), or discrete-event simulation — with classical DoE principles to systematically explore the factor space of a system. Rather than running costly or hazardous physical trials, researchers execute a structured set of virtual experiments across selected factor combinations, then fit a surrogate model to the simulation outputs to understand main effects, interactions, and optimal settings.	Design of Experiments (DOE) is a systematic framework for planning, conducting, and analyzing controlled experiments to determine how multiple input factors simultaneously affect one or more responses. Introduced by Ronald A. Fisher in 1935, DOE allows researchers and engineers to identify causal relationships, quantify factor effects, and find optimal settings efficiently — using far fewer runs than one-factor-at-a-time approaches. It is foundational in engineering, manufacturing, agriculture, and applied sciences.