เปรียบเทียบวิธี

	การกลั่นแบบเกิดปฏิกิริยา	UNIFAC
สาขาวิชา	ฟิสิกส์ประยุกต์	ฟิสิกส์ประยุกต์
ตระกูล	Process / pipeline	Process / pipeline
ปีกำเนิด	1995	1975
ผู้ริเริ่ม	Klaus Sundmacher	Aage Fredenslund, Russell Jones, John Prausnitz
ประเภท	Integrated reaction-separation process model	Activity coefficient model; predictive liquid-phase property method
แหล่งต้นตำรับ	Sundmacher, K., & Kienle, A. (2003). Reactive Distillation: Status and Future Directions. Wiley-VCH. ISBN: 978-3-527-30623-9	Fredenslund, A., Jones, R. L., & Prausnitz, J. M. (1975). Group-contribution estimation of activity coefficients in nonideal liquid mixtures. AIChE Journal, 21(6), 1086-1099.
ชื่อเรียกอื่น	integrated distillation-reaction, reactive column, reaction with separation	UNIFAC predictive model, UNIQUAC functional-group contribution
ที่เกี่ยวข้อง	4	3
สรุป	Reactive distillation couples reaction and separation in a single column, where reactants are separated from products continuously while simultaneously undergoing reaction on catalytic trays. Pioneered in the 1990s by Klaus Sundmacher and others, this process intensification technique dramatically reduces capital cost, energy consumption, and environmental impact for suitable reactions. It is now industrially proven for esterification, hydration, and transesterification processes.	UNIFAC (Universal Functional-group Activity Coefficient) is a predictive model for liquid-phase activity coefficients of multicomponent mixtures. Developed by Fredenslund, Jones, and Prausnitz in 1975, it decomposes molecules into functional groups and uses group interaction parameters to estimate non-ideal behavior. UNIFAC is revolutionary because it can predict phase equilibria for mixtures never experimentally measured, making it invaluable for process design and chemical engineering.