เปรียบเทียบวิธี
ดูวิธีที่เลือกเทียบกันแบบเคียงข้าง แถวที่ต่างกันจะถูกเน้นไว้
| การศึกษากลุ่มควบคุมแบบหลายศูนย์ (Multicenter Case-Control Study)× | การศึกษากลุ่มควบคุมที่ซ้อนกัน (Nested Case-Control Study)× | |
|---|---|---|
| สาขาวิชา | ระบาดวิทยา | ระบาดวิทยา |
| ตระกูล | Process / pipeline | Process / pipeline |
| ปีกำเนิด≠ | Mid-20th century; multicenter framework formalised 1970s–1980s | 1973–1977 |
| ผู้ริเริ่ม≠ | Epidemiology convention; seminal statistical framework by Breslow & Day (IARC, 1980) | Nathan Mantel (1973); D. C. Thomas (1977 formalization) |
| ประเภท≠ | Observational analytical epidemiological design | Hybrid observational study design |
| แหล่งต้นตำรับ≠ | Breslow, N. E., & Day, N. E. (1980). Statistical Methods in Cancer Research. Volume I: The Analysis of Case-Control Studies. IARC Scientific Publications No. 32. International Agency for Research on Cancer, Lyon. ISBN: 978-9283211327 | Thomas, D. C. (1977). Addendum to: Methods of cohort analysis: Appraisal by application to asbestos mining. Journal of the Royal Statistical Society, Series A, 140(4), 469–491. link ↗ |
| ชื่อเรียกอื่น | multisite case-control study, collaborative case-control study, pooled case-control study, multi-institutional case-control study | NCC study, nested CC design, case-control within cohort, density sampling case-control |
| ที่เกี่ยวข้อง | 6 | 6 |
| สรุป≠ | A multicenter case-control study is an observational design that identifies individuals who have developed a disease (cases) and disease-free comparators (controls) across two or more study sites simultaneously. By pooling recruitment across hospitals, clinics, or geographic regions, the design achieves larger sample sizes, captures exposure variability over broader populations, and improves the statistical power needed to detect modest odds ratios for rare or heterogeneous diseases. | A nested case-control study is an efficient observational design embedded within a defined cohort. For each participant who develops the outcome of interest (a case), a small number of matched controls are sampled from those still at risk at the same point in time. This density-sampling strategy yields odds ratios that approximate incidence-rate ratios from the full cohort at a fraction of the data-collection cost — making it the preferred alternative when measuring exposures for all cohort members would be prohibitively expensive or technically demanding. |
| ScholarGateชุดข้อมูล ↗ |
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