เปรียบเทียบวิธี

	การประเมินการทดสอบคัดกรองแบบจับคู่	การศึกษาแบบจับคู่กรณี-ควบคุม
สาขาวิชา	ระบาดวิทยา	ระบาดวิทยา
ตระกูล	Process / pipeline	Process / pipeline
ปีกำเนิด	1980s–2000s (formalized alongside diagnostic accuracy methodology)	1950s–1970s
ผู้ริเริ่ม	Methodological synthesis from matched case-control and diagnostic accuracy traditions (Pepe, Zhou, and others)	Brian MacMahon and others; systematised by Schlesselman (1982)
ประเภท	Observational diagnostic study with matched design	Observational analytic design
แหล่งต้นตำรับ	Pepe, M. S. (2003). The Statistical Evaluation of Medical Tests for Classification and Prediction. Oxford University Press. ISBN: 978-0198509844	Rothman, K. J., Greenland, S., & Lash, T. L. (2008). Modern Epidemiology (3rd ed.). Lippincott Williams & Wilkins. ISBN: 978-0781755474
ชื่อเรียกอื่น	matched diagnostic accuracy study, paired screening evaluation, matched-pair test performance study, matched screening assessment	matched case-referent study, individually matched case-control, pair-matched case-control, matched case-control design
ที่เกี่ยวข้อง	6	5
สรุป	Matched screening test evaluation assesses the sensitivity, specificity, and predictive values of a screening or diagnostic test using a matched design, in which disease-positive cases are paired with one or more disease-free controls selected to share key characteristics such as age, sex, or clinical setting. Matching controls for confounders before measuring test performance produces more precise and less biased estimates of diagnostic accuracy, and enables direct paired comparisons of competing tests within the same subjects.	A matched case-control study is an observational epidemiological design in which each case (a person with the disease or outcome of interest) is paired with one or more controls (persons without the outcome) who share one or more characteristics — such as age, sex, or clinical setting — to control confounding. Exposure history is then compared between cases and their matched controls to estimate the odds ratio of the exposure-disease association.