เปรียบเทียบวิธี

	การออกแบบการทดลองแบบผสมผสาน	การออกแบบการทดลอง
สาขาวิชา	การออกแบบการทดลอง	การออกแบบการทดลอง
ตระกูล	Process / pipeline	Process / pipeline
ปีกำเนิด	1989–2000s	1935
ผู้ริเริ่ม	Multiple contributors; notably Sacks, Welch, Mitchell & Wynn (computer experiments); broader hybrid concept developed across 1980s–2000s	Ronald A. Fisher
ประเภท	Combined experimental design strategy	Experimental planning framework
แหล่งต้นตำรับ	Santner, T. J., Williams, B. J., & Notz, W. I. (2003). The Design and Analysis of Computer Experiments. Springer. ISBN: 978-1441929921	Fisher, R. A. (1935). The Design of Experiments. Oliver and Boyd.
ชื่อเรียกอื่น	hybrid DOE, combined experimental design, mixed experimental design, hybrid experimental strategy	DOE, experimental design, factorial experimentation, planned experimentation
ที่เกี่ยวข้อง	4	3
สรุป	Hybrid design of experiments (hybrid DOE) combines two or more experimental design strategies within a single study to exploit the complementary strengths of each. Common combinations include factorial or fractional-factorial arrays paired with computer simulation runs, space-filling Latin hypercube designs merged with response surface augmentations, or Taguchi orthogonal arrays integrated with response surface methodology. The approach is widely used when a single design type cannot efficiently cover all phases of an engineering investigation — from screening through to optimization.	Design of Experiments (DOE) is a systematic framework for planning, conducting, and analyzing controlled experiments to determine how multiple input factors simultaneously affect one or more responses. Introduced by Ronald A. Fisher in 1935, DOE allows researchers and engineers to identify causal relationships, quantify factor effects, and find optimal settings efficiently — using far fewer runs than one-factor-at-a-time approaches. It is foundational in engineering, manufacturing, agriculture, and applied sciences.