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มุมสัมผัส (Contact Angle) และการวัด×การวิเคราะห์ทางกลพลวัต×การปั่นด้วยไฟฟ้า×การพองตัวและการเสื่อมสลาย×
สาขาวิชาวัสดุชีวภาพวัสดุชีวภาพวัสดุชีวภาพวัสดุชีวภาพ
ตระกูลProcess / pipelineProcess / pipelineProcess / pipelineProcess / pipeline
ปีกำเนิด1805196019341960
ผู้ริเริ่มThomas YoungFerry and SchwarzlAnton FormhalsWichterle and Lim
ประเภทWettability measurementRheological characterizationFiber fabrication processKinetic assay
แหล่งต้นตำรับYoung, T. (1805). An essay on the cohesion of fluids. Philosophical Transactions of the Royal Society, 95, 65-87. link ↗Menard, K. P. (2008). Dynamic mechanical analysis: a practical introduction (2nd ed.). CRC Press. link ↗Formhals, A. (1934). Process and apparatus for preparing artificial threads. U.S. Patent 1,975,504. link ↗Wichterle, O., & Lim, D. (1960). Hydrophilic gels for biological use. Nature, 185(4706), 117-118. DOI ↗
ชื่อเรียกอื่นsessile drop method, contact angle measurement, wettability analysisDMA, rheological analysis, viscoelastic testingelectrospun fiber production, electrostatic fiber spinninghydrogel swelling, polymer degradation, mass loss assay
ที่เกี่ยวข้อง3334
สรุปContact angle goniometry is a technique for measuring the wettability of a solid surface by determining the angle at which a liquid droplet meets the surface. Rooted in Thomas Young's thermodynamic analysis from 1805, the method uses optical measurement of droplet profile to quantify surface energy and hydrophilicity. It is indispensable in biomaterials characterization, helping researchers assess whether a scaffold or implant surface will promote or inhibit cell adhesion, protein adsorption, and biointegration.Dynamic mechanical analysis (DMA) measures the viscoelastic properties of materials—their elastic stiffness and viscous damping—by applying a sinusoidal stress or strain and measuring the phase lag and amplitude of the material's response. Developed from rheology principles in the 1960s and formalized by Ferry, Schwarzl, and others, DMA provides quantitative measures of how polymeric biomaterials respond to time-dependent and frequency-dependent mechanical stimuli. Key outputs include the storage modulus (elastic component), loss modulus (viscous component), and loss tangent (tan δ), which together characterize the material's mechanical behavior across temperature and frequency ranges.Electrospinning is an electrostatic fiber fabrication process that uses a high electric field to draw polymer solutions or melts into nanoscale fibers. Developed by Anton Formhals in the 1930s and refined by researchers including Darrell Reneker in the 1990s, the technique has become foundational to biomaterials engineering, enabling the creation of porous scaffolds for tissue engineering and drug delivery systems.The swelling and degradation assay measures how biomaterial scaffolds absorb water (swelling) and lose mass over time due to degradation. Developed by Wichterle and Lim in 1960 for hydrogels, the assay is fundamental for characterizing hydrogels, synthetic polymers, and composite scaffolds intended for tissue engineering. The assay provides quantitative data on swelling kinetics (equilibrium water content, swelling ratio), degradation kinetics (mass loss rate, half-life), and mechanisms of degradation (chain scission, enzymatic breakdown).
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ScholarGateเปรียบเทียบวิธี: Contact Angle Goniometry · Dynamic Mechanical Analysis · Electrospinning · Swelling and Degradation. สืบค้นเมื่อ 2026-06-19 จาก https://scholargate.app/th/compare