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Process / pipelineSelf-controlled causal designs / pharmacoepidemiology

Self-Controlled Case Series

The self-controlled case series, or SCCS, is a case-only study design for estimating the association between a transient exposure and an acute event by comparing each individual's event rate during exposed time windows with their rate during unexposed time windows. Developed by Paddy Farrington in 1995 for vaccine safety evaluation, it uses data only on people who experienced the outcome, and because each person serves as their own control, it automatically eliminates all fixed within-person confounders — genetics, sex, chronic conditions, socioeconomic position — without ever measuring them. A conditional Poisson likelihood removes the individual-level baseline rate and yields a relative incidence comparing risk to control periods. Whitaker, Farrington, Spiessens and Musonda's 2006 Statistics in Medicine tutorial is the standard practical guide to fitting and interpreting the model.

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Self-Controlled Case Series
Case-Time-Control DesignNegative Control Outcome…Poisson Rate RegressionMfululizo wa Kesi wa Kib…Muundo wa Kesi-Msalaba w…Muundo wa Kesi-MsalabaInterrupted Time Series…Muundo Ulinganifu wa Kes…Muundo wa Uchunguzi wa B…

Vyanzo

  1. Farrington, C. P. (1995). Relative Incidence Estimation from Case Series for Vaccine Safety Evaluation. Biometrics, 51(1), 228-235. DOI: 10.2307/2533328 ↗
  2. Whitaker, H. J., Farrington, C. P., Spiessens, B., & Musonda, P. (2006). Tutorial in Biostatistics: The Self-Controlled Case Series Method. Statistics in Medicine, 25(10), 1768-1797. DOI: 10.1002/sim.2302 ↗

Jinsi ya kunukuu ukurasa huu

ScholarGate. (2026, June 23). Self-Controlled Case Series (Within-Person Relative Incidence of Acute Events After Transient Exposures). ScholarGate. https://scholargate.app/sw/social-epidemiology/self-controlled-case-series

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Imerejelewa na

Mfululizo wa Kesi wa KibayesianiMuundo wa Kesi-Msalaba wa BayesianMuundo wa Kesi-MsalabaCase-Time-Control DesignInterrupted Time Series for Public HealthMuundo Ulinganifu wa Kesi-MsalabaNegative Control Outcome DesignPoisson Rate RegressionMuundo wa Uchunguzi wa Baadaye wa Kesi-Msalaba

Mbinu zinazofanana

Bayesian Case SeriesProspective Case-Crossover DesignRisk-adjusted case-crossover designCase-crossover designMatched Case-Crossover DesignCase-Time-Control DesignMulticenter Case-Crossover DesignBayesian Case-Crossover Design

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Utafiti wa Kesi-udhibitiMatukio Mabaya Makubwa Yasiyo Ya Kawaida na Tathmini ya HatariUtafiti wa Matukio Mabaya na Ufuatiliaji wa DawaUtafiti wa CohortUtafiti wa Kesi-Udhibiti na Kundi la Watu katika Uchunguzi wa MlipukoUfuatiliaji na Taarifa za Matukio Baada ya Chanjo

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ScholarGate — Self-Controlled Case Series (Self-Controlled Case Series (Within-Person Relative Incidence of Acute Events After Transient Exposures)). Imepatikana 2026-06-24 kutoka https://scholargate.app/sw/social-epidemiology/self-controlled-case-series · Seti ya data: https://doi.org/10.5281/zenodo.20539026