Linganisha mbinu

	Makadirio Yanayolengwa ya Uwezekano wa Juu Zaidi (TMLE)	Uzito wa Kinyume wa Uwezekano wa Matibabu (IPW / IPTW)
Nyanja	Uhitimisho wa Kisababishi	Uhitimisho wa Kisababishi
Familia	Machine learning	Regression model
Mwaka wa asili	2006	2000
Mwanzilishi	Mark van der Laan & Daniel Rubin	Robins, Hernán & Brumback
Aina	Semiparametric estimator	Causal inference weighting estimator
Chanzo asilia	van der Laan, M. J., & Rubin, D. (2006). Targeted maximum likelihood learning. The International Journal of Biostatistics, 2(1).	Robins, J. M., Hernán, M. A., & Brumback, B. (2000). Marginal Structural Models and Causal Inference in Epidemiology. Epidemiology, 11(5), 550-560.
Majina mbadala	Targeted Learning, TMLE, Targeted MLE, Hedeflenmiş Maksimum Olabilirlik Tahmini	IPW, IPTW, inverse probability of treatment weighting, marginal structural model weighting
Zinazohusiana	3	5
Muhtasari	Targeted Maximum Likelihood Estimation (TMLE) is a semiparametric, doubly robust causal inference method introduced by Mark van der Laan and Daniel Rubin in 2006. It combines flexible machine learning models for both the outcome and the treatment assignment mechanism, then applies a targeting step that re-fits the initial outcome model specifically to reduce bias for a pre-specified causal estimand such as the average treatment effect. TMLE is widely used in epidemiology, biostatistics, and health economics when estimating causal effects from observational data.	Inverse Probability Weighting is a causal-inference method that assigns each observation a weight equal to the inverse of its probability of receiving the treatment it actually received. Introduced by Robins, Hernán and Brumback (2000) for marginal structural models, it builds a pseudo-population in which treatment is independent of measured confounders, balancing selection bias.