Linganisha mbinu

	MSFC: Kipimo Jumuishi cha Utendaji Kazi wa Sclerosis Nyingi	EDSS: Kurtzke Expanded Disability Status Scale	MDS-UPDRS	RMI: Kielelezo cha Uhamaji cha Rivermead
Nyanja	Neurolojia	Neurolojia	Neurolojia	Neurolojia
Familia	Process / pipeline	Process / pipeline	Process / pipeline	Process / pipeline
Mwaka wa asili	1999	1983	2008	1991
Mwanzilishi	Gary Cutter, Richard Rudick, and NMSS Consortium	John F. Kurtzke	Christopher G. Goetz and Movement Disorder Society	Frank Collen, Derick Wade, and Rivermead Rehabilitation Centre
Aina	Clinician-administered performance test	Clinician-rated	Clinician-rated	Clinician-observed performance test
Chanzo asilia	Cutter, G. R., Baier, M. L., Rudick, R. A., et al. (1999). Development of a multiple sclerosis functional composite as a clinical trial outcome measure. Multiple Sclerosis, 5(4), 244-250.	Kurtzke, J. F. (1983). Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS). Neurology, 33(11), 1444-1452.	Goetz, C. G., et al. (2008). Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): Scale presentation and clinimetric testing results. Movement Disorders, 23(15), 2129-2170.	Collen, F. M., Wade, D. T., Robb, G. F., Bradshaw, C. M. (1991). The Rivermead Mobility Index: A further development of the Rivermead Motor Assessment. International Disability Studies, 13(2), 50-54.
Majina mbadala	MS Functional Composite	Expanded Disability Status Scale	UPDRS	Rivermead Mobility Index
Zinazohusiana	4	4	5	5
Muhtasari	The Multiple Sclerosis Functional Composite (MSFC) is an objective, performance-based assessment of MS-related disability capturing three key functional domains: lower extremity mobility, upper extremity coordination, and cognitive/processing speed. Developed in 1999 by the National MS Society and adopted widely in clinical trials, the MSFC provides quantifiable endpoints complementing the Expanded Disability Status Scale (EDSS). The three-component design addresses EDSS limitations by including cognition and standardizing measurement via timed tasks.	The EDSS is the most widely used clinical disability rating scale in multiple sclerosis research and practice. Developed by John Kurtzke in 1983, it provides a 0-10 ordinal scale capturing disease severity across eight neurological functional systems and functional status. The EDSS remains the primary endpoint in MS clinical trials and longitudinal cohort studies, with decades of prognostic and comparative data worldwide.	The MDS-UPDRS is the gold-standard clinician-administered rating scale for assessing motor and non-motor manifestations of Parkinson's disease. Developed by the Movement Disorder Society in 2008 to enhance the original UPDRS, it measures disease severity across daily living, motor function, and treatment complications. Used globally in clinical trials, longitudinal cohort studies, and routine neurological practice.	The Rivermead Mobility Index (RMI) is a brief, clinician-observed performance test of basic mobility abilities developed for assessing stroke and neurological rehabilitation outcomes. Published in 1991 by Frank Collen and colleagues at Rivermead Rehabilitation Centre (Oxford, UK), the 15-item index measures bed mobility, sitting/standing balance, transfers, and ambulation. The RMI is widely used in stroke units and rehabilitation settings to track functional recovery and predict discharge outcomes.