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Muundo Unaobadilika wa Jaribio la Kliniki×Uchambuzi wa Nguvu×
NyanjaMuundo wa MajaribioTakwimu
FamiliaHypothesis testHypothesis test
Mwaka wa asili19941969 (1st ed.); 1988 (seminal 2nd ed.)
MwanzilishiBauer & KöhneJacob Cohen
AinaAdaptive hypothesis test with interim analysesSample size and power planning
Chanzo asiliaBauer, P. & Köhne, K. (1994). Evaluation of Experiments with Adaptive Interim Analyses. Biometrics, 50(4), 1029–1041. DOI ↗Cohen, J. (1988). Statistical Power Analysis for the Behavioral Sciences (2nd ed.). Lawrence Erlbaum Associates. ISBN: 978-0805802832
Majina mbadalaadaptive design, group sequential design, sample size re-estimation, platform trialsample size calculation, power calculation, sensitivity analysis, a priori power analysis
Zinazohusiana35
MuhtasariAdaptive clinical trial design is a flexible experimental framework, formalised by Bauer and Köhne in 1994, in which pre-specified rules allow the trial to be modified mid-course — adjusting sample size, treatment arms, or randomisation ratios — based on accumulating interim data while rigorously controlling the Type I error rate.Power analysis is a planning and evaluation technique that quantifies the probability of detecting a real effect of a given magnitude at a chosen significance level. It links four quantities — sample size, effect size, significance level (alpha), and statistical power (1 minus beta) — so that researchers can determine the sample size needed before data collection or evaluate the sensitivity of a completed study.
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ScholarGateLinganisha mbinu: Adaptive Clinical Trial Design · Power analysis. Imepatikana 2026-06-18 kutoka https://scholargate.app/sw/compare